INNOCENT NNAMDI IJEOMA

INNOCENT NNAMDI IJEOMA

Specialist Medical Representative at Novartis Global Health

Nexford University, Washington DC

Nigeria

AboutEventsChannelsCommunities

Hi, I'm INNOCENT NNAMDI IJEOMA!

Specialist Medical Representative at Novartis Global Health

I am a goal getter, always wanting to be the best in anything I do, poised to deliver results and eager to learn something new every single day, I can adapt quickly in any fast paced industry, I am superb in analytical thinking, problem solving, critical reasoning and technology application. I am a great team player/leader. A passionate, upstanding, responsible and detail-oriented Pharmacist, open to new challenges in any dynamic, progressive organisation. My relevant experience gathered over the years and the company's professional offerings, will ensure a win-win situation in my professional advancement and the organization meeting its objectives.

Socials

Experience

Education

Certificates & Badges

No certificates or badges added

Projects

Suppressive and curative antiplasmodial properties of Nauclea latifolia root extract and fractions against erythrocytic stage of

https://jomped.org/index.php/jomped/rt/printerFriendly/72/277

Junior Researcher

Abstract

Background: Malaria remains a devastating disease, particularly in the tropics, where it is the highest killer of pregnant women and children under the age of 5 years. Significant efforts and resources have been vested in malaria control and eradication programmes, but the unavailability of malaria vaccine and the emergence of resistance of malaria parasite to existing antimalarial drugs have continued to hamper attempts at controlling or eradicating the disease. This warrants the development of new antimalarial drugs. Nauclea latifolia root is widely applied for malaria treatment in Nigeria.

Aim: This study investigated the antimalarial property of N. latifolia roots.

Setting: N. latifolia roots were collected from Ikwuano, Umuahia, Abia State, Nigeria.

Methods: To extract the bioactive constituents, an aqueous infusion of the plant was prepared and fractionated by solvent-solvent extraction with n-hexane, ethyl acetate and butanol, respectively. Antimalarial property was evaluated using suppressive and curative assays in mice infected with chloroquine-sensitive Plasmodium berghei NK-65 strain.

Results: The extract and fractions produced significant suppressive and curative antiplasmodial activities (p < 0.05). The aqueous extract and n-hexane and butanol fractions gave 85.22%, 84.52% and 91.32% chemosuppression, respectively, which were comparable to that of chloroquine used as positive control. The extract and fractions gave considerable curative effects in the range 52.23% – 77.00%.

Conclusion: These findings indicate that N. latifolia roots possess antimalarial property and reflect its ethnomedicinal use for malaria treatment. Thus, N. latifolia roots may be exploited for development of herbal formulations and isolation of novel bioactive compounds for malaria treatment.

Keywords: antimalarial; antiplasmodial; suppressive activity; curative activity; Plasmodium berghei; Nauclea latifolia.

Languages

English

Skills

Brand Awareness

Branding Strategy & Planning

Marketing Effectiveness, Increasing

Community Health

Negotiation on Benefits

Localized connects university students and recent graduates with industry experts and employers.

ProductStudentsEmployersUniversities

PrivacyTermsSitemap

©2025 Localized, Inc. All rights reserved.

Ready for a personalized experience? We use cookies and similar technologies to tailor our site just for you. By clicking 'Accept', you're giving us the thumbs up to use cookies and similar technologies. 🍪